Health

EXPLAINER: What we all know and don’t know on new COVID variant

LONDON — South African scientists recognized a brand new model of the coronavirus that they are saying is behind a current spike in COVID-19 infections in Gauteng, the nation’s most populous province.

It’s unclear the place the brand new variant first emerged, however scientists in South Africa alerted the World Well being Group in current days, and it has now been seen in vacationers arriving in a number of nations, from Australia to Israel to the Netherlands.

On Friday, the WHO designated it as a “variant of concern,” naming it “omicron” after a letter within the Greek alphabet.

WHAT DO WE KNOW ABOUT OMICRON?

Well being Minister Joe Phaahla stated the variant was linked to an “exponential rise” of instances in the previous couple of days.

From simply over 200 new confirmed instances per day in current weeks, South Africa noticed the variety of new each day instances rocket to greater than 3,200 Saturday, most in Gauteng.

Struggling to clarify the sudden rise in instances, scientists studied virus samples and found the brand new variant. Now, as many as 90% of the brand new instances in Gauteng are attributable to it, according to Tulio de Oliveira, director of the KwaZulu-Natal Analysis Innovation and Sequencing Platform.

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WHY ARE SCIENTISTS WORRIED ABOUT THIS NEW VARIANT?

After convening a gaggle of specialists to evaluate the info, the WHO stated that “preliminary proof suggests an elevated threat of reinfection with this variant,” as in comparison with different variants.

Which means individuals who contracted COVID-19 and recovered could possibly be topic to catching it once more.

The variant seems to have a excessive variety of mutations — about 30 — within the coronavirus’ spike protein, which might have an effect on how simply it spreads to folks.

Sharon Peacock, who has led genetic sequencing of COVID-19 in Britain on the College of Cambridge, stated the info to date recommend the brand new variant has mutations “per enhanced transmissibility,” however stated that “the importance of lots of the mutations remains to be not identified.”

Lawrence Younger, a virologist on the College of Warwick, described omicron as “probably the most closely mutated model of the virus we’ve got seen,” together with probably worrying modifications by no means earlier than seen all in the identical virus.

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WHAT’S KNOWN AND NOT KNOWN ABOUT THE VARIANT?

Scientists know that omicron is genetically distinct from earlier variants together with the beta and delta variants, however have no idea if these genetic modifications make it any extra transmissible or harmful. To date, there is no such thing as a indication the variant causes extra extreme illness.

It should doubtless take weeks to kind out if omicron is extra infectious and if vaccines are nonetheless efficient in opposition to it.

Peter Openshaw, a professor of experimental medication at Imperial School London stated it was “extraordinarily unlikely” that present vaccines wouldn’t work, noting they’re efficient in opposition to quite a few different variants.

Regardless that a few of the genetic modifications in omicron seem worrying, it’s nonetheless unclear if they are going to pose a public well being risk. Some earlier variants, just like the beta variant, initially alarmed scientists however didn’t find yourself spreading very far.

“We don’t know if this new variant might get a toehold in areas the place delta is,” stated Peacock of the College of Cambridge. “The jury is out on how nicely this variant will do the place there are different variants circulating.”

So far, delta is by far probably the most predominant type of COVID-19, accounting for greater than 99% of sequences submitted to the world’s largest public database.

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HOW DID THIS NEW VARIANT ARISE?

The coronavirus mutates because it spreads and lots of new variants, together with these with worrying genetic modifications, typically simply die out. Scientists monitor COVID-19 sequences for mutations that might make the illness extra transmissible or lethal, however they can not decide that just by wanting on the virus.

Peacock stated the variant “could have developed in somebody who was contaminated however might then not clear the virus, giving the virus the possibility to genetically evolve,” in a situation much like how specialists suppose the alpha variant — which was first recognized in England — additionally emerged, by mutating in an immune-compromised particular person.

ARE THE TRAVEL RESTRICTIONS BEING IMPOSED BY SOME COUNTRIES JUSTIFIED?

Possibly.

Israel is banning foreigners from coming into the nation and Morocco has stopped all incoming worldwide air journey.

Various different nations are limiting flights in from southern Africa.

Given the current speedy rise in COVID-19 in South Africa, limiting journey from the area is “prudent” and would purchase authorities extra time, stated Neil Ferguson, an infectious illnesses professional at Imperial School London.

However the WHO famous that such restrictions are sometimes restricted of their impact and urged nations to maintain borders open.

Jeffrey Barrett, director of COVID-19 Genetics on the Wellcome Sanger Institute, thought that the early detection of the brand new variant might imply restrictions taken now would have a much bigger affect than when the delta variant first emerged.

“With delta, it took many, many weeks into India’s horrible wave earlier than it grew to become clear what was occurring and delta had already seeded itself in lots of locations on this planet and it was too late to do something about it,” he stated. “We could also be at an earlier level with this new variant so there should be time to do one thing about it.”

South Africa’s authorities stated the nation was being handled unfairly as a result of it has superior genomic sequencing and will detect the variant faster and requested different nations to rethink the journey bans.

Dr. Matshidiso Moeti, WHO’s regional director for Africa, counseled South Africa and Botswana for rapidly informing the world concerning the new variant.

“With the omicron variant now detected in a number of areas of the world, putting in journey bans that focus on Africa assaults world solidarity,” Moeti stated. “COVID-19 continually exploits our divisions. We’ll solely get the higher of the virus if we work collectively for options.”

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